Friday, March 19, 2010

Research on Svetol

Green Coffee CherriesSvetol is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol has also been the subject of preliminary clinical studies that have shown exciting results.

In a pilot study, the effect of Svetol on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol and the second OGTT was performed on day 2, after beginning the Svetol regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing.


The results showed that Svetol was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period.

Based on the studies mentioned above and other related research on the ingredients in Svetol, scientists have proposed two mechanisms of action whereby Svetol may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption.

The second mechanism relates to possible effects of Svetol in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.

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